tissue microarray (tma) blocks (SuperBioChips)
90
Structured Review
SuperBioChips
tissue microarray (tma) blocks
Tissue Microarray (Tma) Blocks, supplied by SuperBioChips, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/tissue+microarray+(tma)+blocks/tissue+microarray++tma++slides/pmc11648117-70-14-18
Average 90 stars, based on 1 article reviews
Tissue Microarray (Tma) Blocks, supplied by SuperBioChips, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/tissue+microarray+(tma)+blocks/tissue+microarray++tma++slides/pmc11648117-70-14-18
Average 90 stars, based on 1 article reviews
tissue microarray (tma) blocks - by Bioz Stars,
2026-10
90/100 stars
Images
1) Product Images from "Clinicopathological analysis of claudin 18.2 focusing on intratumoral heterogeneity and survival in patients with metastatic or unresectable gastric cancer"
Article Title: Clinicopathological analysis of claudin 18.2 focusing on intratumoral heterogeneity and survival in patients with metastatic or unresectable gastric cancer
Journal: ESMO Open
doi: 10.1016/j.esmoop.2024.104000
Figure Legend Snippet: Schematic of the study design. TMA construction (four cores in each case) was carried out in 286 surgically resected samples, and whole-section slides were used in 114 biopsy samples. Among 286 surgically resected samples, immunohistochemistry on whole-section slides was additionally done in 85 cases to compare between TMA and whole-section slides. CLDN18.2, claudin 18.2; GC, gastric cancer; TMA, tissue microarray.
Techniques Used: Immunohistochemistry, Microarray
Figure Legend Snippet: CLDN18.2 positivity in individual TMA cores and intratumoral heterogeneity. (A) CLDN18.2 positivity rates in each single TMA core (cores A, B, C, and D), as well as the positivity rate in at least one of these cores (positive in ≥1 core). (B) The results of CLDN18.2 immunohistochemistry in 111 cases where CLDN18.2 was positive in at least one core. Homogeneous positivity in all four TMA cores was observed in 43 cases (38.7%) and heterogeneous positivity (different results between TMA cores) occurred in the remaining 68 cases (61.3%). CLDN18.2, claudin 18.2; TMA, tissue microarray.
Techniques Used: Immunohistochemistry, Microarray
Related Articles
Construct:Article Title: Clinicopathologic significance of human leukocyte antigen class I expression in patients with stage II and III gastric cancer. Article Snippet: Human leukocyte antigen class I (HLA I) molecules composed of alpha (heavy) chain, including HLA-A, -B, or -C encoded by HLA genes, and beta-2-microglobulin (β2M) are membrane proteins on all nucleated cells that display peptide antigens for recognition by CD8-positive cytotoxic T cells.. Here, we examined the clinicopathologic signification of HLA I expression in patients with gastric cancer (GC).. Immunohistochemistry was performed to detect HLA A/B/C, β2M, CD8, p53, and programmed death-ligand 1 (PD-L1) in the center and invasive margin of the tumor in 395 stage II and III GCs using tissue array method. Article Title: Central neurocytoma exhibits radial glial cell signatures with FGFR3 hypomethylation and overexpression. Article Snippet: Article Title: Clinicopathological analysis of claudin 18.2 focusing on intratumoral heterogeneity and survival in patients with metastatic or unresectable gastric cancer. Article Snippet: Tissue sample selection and tissue microarray construction Of the 400 advanced GC cases, 286 surgically collected samples were used to construct tissue microarray (TMA) blocks ( Article Title: An immunohistochemical panel consisting of EZH2, C-KIT, and CD205 is useful for distinguishing thymic squamous cell carcinoma from type B3 thymoma. Article Snippet: Type B3 thymoma and thymic squamous cell carcinoma (SqCC) often cause a diagnostic problem due to their histological similarities.. The aim of this study is to identify EZH2 as a novel and powerful biomarker that can effectively distinguish thymic SqCC from type B3 thymoma, and find optimal combinations among 11 markers.. A total of 53 patients, comprising 26 with type B3 thymoma and 27 with thymic SqCC, were allocated to the discovery or validation cohorts, and immunohistochemical staining was performed and analyzed. Article Title: Central neurocytoma exhibits radial glial cell signatures with FGFR3 hypomethylation and overexpression Article Snippet: Article Title: Clinicopathologic significance of human leukocyte antigen class I expression in patients with stage II and III gastric cancer Article Snippet: Tissue microarray (TMA) blocks were designed as described previously ( Article Title: Clinicopathological analysis of claudin 18.2 focusing on intratumoral heterogeneity and survival in patients with metastatic or unresectable gastric cancer Article Snippet: Of the 400 advanced GC cases, 286 surgically collected samples were used to construct Article Title: Bcl-6-dependent risk stratification by nuclear expression of Peli1 in diffuse large B-cell lymphoma Article Snippet: Microarray:Article Title: Clinicopathologic significance of human leukocyte antigen class I expression in patients with stage II and III gastric cancer. Article Snippet: Human leukocyte antigen class I (HLA I) molecules composed of alpha (heavy) chain, including HLA-A, -B, or -C encoded by HLA genes, and beta-2-microglobulin (β2M) are membrane proteins on all nucleated cells that display peptide antigens for recognition by CD8-positive cytotoxic T cells.. Here, we examined the clinicopathologic signification of HLA I expression in patients with gastric cancer (GC).. Immunohistochemistry was performed to detect HLA A/B/C, β2M, CD8, p53, and programmed death-ligand 1 (PD-L1) in the center and invasive margin of the tumor in 395 stage II and III GCs using tissue array method. Article Title: Central neurocytoma exhibits radial glial cell signatures with FGFR3 hypomethylation and overexpression. Article Snippet: Article Title: Clinicopathological analysis of claudin 18.2 focusing on intratumoral heterogeneity and survival in patients with metastatic or unresectable gastric cancer. Article Snippet: Tissue sample selection and tissue microarray construction Of the 400 advanced GC cases, 286 surgically collected samples were used to construct tissue microarray (TMA) blocks ( Article Title: An immunohistochemical panel consisting of EZH2, C-KIT, and CD205 is useful for distinguishing thymic squamous cell carcinoma from type B3 thymoma. Article Snippet: Type B3 thymoma and thymic squamous cell carcinoma (SqCC) often cause a diagnostic problem due to their histological similarities.. The aim of this study is to identify EZH2 as a novel and powerful biomarker that can effectively distinguish thymic SqCC from type B3 thymoma, and find optimal combinations among 11 markers.. A total of 53 patients, comprising 26 with type B3 thymoma and 27 with thymic SqCC, were allocated to the discovery or validation cohorts, and immunohistochemical staining was performed and analyzed. Article Title: Central neurocytoma exhibits radial glial cell signatures with FGFR3 hypomethylation and overexpression Article Snippet: Article Title: Clinicopathologic significance of human leukocyte antigen class I expression in patients with stage II and III gastric cancer Article Snippet: Tissue microarray (TMA) blocks were designed as described previously ( Article Title: Clinicopathological analysis of claudin 18.2 focusing on intratumoral heterogeneity and survival in patients with metastatic or unresectable gastric cancer Article Snippet: Of the 400 advanced GC cases, 286 surgically collected samples were used to construct Article Title: Bcl-6-dependent risk stratification by nuclear expression of Peli1 in diffuse large B-cell lymphoma Article Snippet: Immunohistochemistry:Article Title: Clinicopathologic significance of human leukocyte antigen class I expression in patients with stage II and III gastric cancer. Article Snippet: Human leukocyte antigen class I (HLA I) molecules composed of alpha (heavy) chain, including HLA-A, -B, or -C encoded by HLA genes, and beta-2-microglobulin (β2M) are membrane proteins on all nucleated cells that display peptide antigens for recognition by CD8-positive cytotoxic T cells.. Here, we examined the clinicopathologic signification of HLA I expression in patients with gastric cancer (GC).. Immunohistochemistry was performed to detect HLA A/B/C, β2M, CD8, p53, and programmed death-ligand 1 (PD-L1) in the center and invasive margin of the tumor in 395 stage II and III GCs using tissue array method. Article Title: Central neurocytoma exhibits radial glial cell signatures with FGFR3 hypomethylation and overexpression. Article Snippet: Article Title: Clinicopathological analysis of claudin 18.2 focusing on intratumoral heterogeneity and survival in patients with metastatic or unresectable gastric cancer. Article Snippet: Tissue sample selection and tissue microarray construction Of the 400 advanced GC cases, 286 surgically collected samples were used to construct tissue microarray (TMA) blocks ( Article Title: An immunohistochemical panel consisting of EZH2, C-KIT, and CD205 is useful for distinguishing thymic squamous cell carcinoma from type B3 thymoma. Article Snippet: Type B3 thymoma and thymic squamous cell carcinoma (SqCC) often cause a diagnostic problem due to their histological similarities.. The aim of this study is to identify EZH2 as a novel and powerful biomarker that can effectively distinguish thymic SqCC from type B3 thymoma, and find optimal combinations among 11 markers.. A total of 53 patients, comprising 26 with type B3 thymoma and 27 with thymic SqCC, were allocated to the discovery or validation cohorts, and immunohistochemical staining was performed and analyzed. Article Title: Central neurocytoma exhibits radial glial cell signatures with FGFR3 hypomethylation and overexpression Article Snippet: Article Title: Clinicopathologic significance of human leukocyte antigen class I expression in patients with stage II and III gastric cancer Article Snippet: Tissue microarray (TMA) blocks were designed as described previously ( Article Title: Clinicopathological analysis of claudin 18.2 focusing on intratumoral heterogeneity and survival in patients with metastatic or unresectable gastric cancer Article Snippet: Of the 400 advanced GC cases, 286 surgically collected samples were used to construct Article Title: Bcl-6-dependent risk stratification by nuclear expression of Peli1 in diffuse large B-cell lymphoma Article Snippet: Selection:Article Title: Clinicopathologic significance of human leukocyte antigen class I expression in patients with stage II and III gastric cancer. Article Snippet: Human leukocyte antigen class I (HLA I) molecules composed of alpha (heavy) chain, including HLA-A, -B, or -C encoded by HLA genes, and beta-2-microglobulin (β2M) are membrane proteins on all nucleated cells that display peptide antigens for recognition by CD8-positive cytotoxic T cells.. Here, we examined the clinicopathologic signification of HLA I expression in patients with gastric cancer (GC).. Immunohistochemistry was performed to detect HLA A/B/C, β2M, CD8, p53, and programmed death-ligand 1 (PD-L1) in the center and invasive margin of the tumor in 395 stage II and III GCs using tissue array method. Article Title: Central neurocytoma exhibits radial glial cell signatures with FGFR3 hypomethylation and overexpression. Article Snippet: Article Title: Clinicopathological analysis of claudin 18.2 focusing on intratumoral heterogeneity and survival in patients with metastatic or unresectable gastric cancer. Article Snippet: Tissue sample selection and tissue microarray construction Of the 400 advanced GC cases, 286 surgically collected samples were used to construct tissue microarray (TMA) blocks ( Article Title: An immunohistochemical panel consisting of EZH2, C-KIT, and CD205 is useful for distinguishing thymic squamous cell carcinoma from type B3 thymoma. Article Snippet: Type B3 thymoma and thymic squamous cell carcinoma (SqCC) often cause a diagnostic problem due to their histological similarities.. The aim of this study is to identify EZH2 as a novel and powerful biomarker that can effectively distinguish thymic SqCC from type B3 thymoma, and find optimal combinations among 11 markers.. A total of 53 patients, comprising 26 with type B3 thymoma and 27 with thymic SqCC, were allocated to the discovery or validation cohorts, and immunohistochemical staining was performed and analyzed. Article Title: Central neurocytoma exhibits radial glial cell signatures with FGFR3 hypomethylation and overexpression Article Snippet: Article Title: Clinicopathologic significance of human leukocyte antigen class I expression in patients with stage II and III gastric cancer Article Snippet: Tissue microarray (TMA) blocks were designed as described previously ( Article Title: Clinicopathological analysis of claudin 18.2 focusing on intratumoral heterogeneity and survival in patients with metastatic or unresectable gastric cancer Article Snippet: Of the 400 advanced GC cases, 286 surgically collected samples were used to construct Article Title: Bcl-6-dependent risk stratification by nuclear expression of Peli1 in diffuse large B-cell lymphoma Article Snippet: Formalin-fixed Paraffin-Embedded:Article Title: Clinicopathologic significance of human leukocyte antigen class I expression in patients with stage II and III gastric cancer. Article Snippet: Human leukocyte antigen class I (HLA I) molecules composed of alpha (heavy) chain, including HLA-A, -B, or -C encoded by HLA genes, and beta-2-microglobulin (β2M) are membrane proteins on all nucleated cells that display peptide antigens for recognition by CD8-positive cytotoxic T cells.. Here, we examined the clinicopathologic signification of HLA I expression in patients with gastric cancer (GC).. Immunohistochemistry was performed to detect HLA A/B/C, β2M, CD8, p53, and programmed death-ligand 1 (PD-L1) in the center and invasive margin of the tumor in 395 stage II and III GCs using tissue array method. Article Title: Central neurocytoma exhibits radial glial cell signatures with FGFR3 hypomethylation and overexpression. Article Snippet: Article Title: Clinicopathological analysis of claudin 18.2 focusing on intratumoral heterogeneity and survival in patients with metastatic or unresectable gastric cancer. Article Snippet: Tissue sample selection and tissue microarray construction Of the 400 advanced GC cases, 286 surgically collected samples were used to construct tissue microarray (TMA) blocks ( Article Title: An immunohistochemical panel consisting of EZH2, C-KIT, and CD205 is useful for distinguishing thymic squamous cell carcinoma from type B3 thymoma. Article Snippet: Type B3 thymoma and thymic squamous cell carcinoma (SqCC) often cause a diagnostic problem due to their histological similarities.. The aim of this study is to identify EZH2 as a novel and powerful biomarker that can effectively distinguish thymic SqCC from type B3 thymoma, and find optimal combinations among 11 markers.. A total of 53 patients, comprising 26 with type B3 thymoma and 27 with thymic SqCC, were allocated to the discovery or validation cohorts, and immunohistochemical staining was performed and analyzed. Article Title: Central neurocytoma exhibits radial glial cell signatures with FGFR3 hypomethylation and overexpression Article Snippet: Article Title: Clinicopathologic significance of human leukocyte antigen class I expression in patients with stage II and III gastric cancer Article Snippet: Tissue microarray (TMA) blocks were designed as described previously ( Article Title: Clinicopathological analysis of claudin 18.2 focusing on intratumoral heterogeneity and survival in patients with metastatic or unresectable gastric cancer Article Snippet: Of the 400 advanced GC cases, 286 surgically collected samples were used to construct Article Title: Bcl-6-dependent risk stratification by nuclear expression of Peli1 in diffuse large B-cell lymphoma Article Snippet: Blocking Assay:Article Title: Clinicopathologic significance of human leukocyte antigen class I expression in patients with stage II and III gastric cancer. Article Snippet: Human leukocyte antigen class I (HLA I) molecules composed of alpha (heavy) chain, including HLA-A, -B, or -C encoded by HLA genes, and beta-2-microglobulin (β2M) are membrane proteins on all nucleated cells that display peptide antigens for recognition by CD8-positive cytotoxic T cells.. Here, we examined the clinicopathologic signification of HLA I expression in patients with gastric cancer (GC).. Immunohistochemistry was performed to detect HLA A/B/C, β2M, CD8, p53, and programmed death-ligand 1 (PD-L1) in the center and invasive margin of the tumor in 395 stage II and III GCs using tissue array method. Article Title: Central neurocytoma exhibits radial glial cell signatures with FGFR3 hypomethylation and overexpression. Article Snippet: Article Title: Clinicopathological analysis of claudin 18.2 focusing on intratumoral heterogeneity and survival in patients with metastatic or unresectable gastric cancer. Article Snippet: Tissue sample selection and tissue microarray construction Of the 400 advanced GC cases, 286 surgically collected samples were used to construct tissue microarray (TMA) blocks ( Article Title: An immunohistochemical panel consisting of EZH2, C-KIT, and CD205 is useful for distinguishing thymic squamous cell carcinoma from type B3 thymoma. Article Snippet: Type B3 thymoma and thymic squamous cell carcinoma (SqCC) often cause a diagnostic problem due to their histological similarities.. The aim of this study is to identify EZH2 as a novel and powerful biomarker that can effectively distinguish thymic SqCC from type B3 thymoma, and find optimal combinations among 11 markers.. A total of 53 patients, comprising 26 with type B3 thymoma and 27 with thymic SqCC, were allocated to the discovery or validation cohorts, and immunohistochemical staining was performed and analyzed. Article Title: Central neurocytoma exhibits radial glial cell signatures with FGFR3 hypomethylation and overexpression Article Snippet: Article Title: Clinicopathologic significance of human leukocyte antigen class I expression in patients with stage II and III gastric cancer Article Snippet: Tissue microarray (TMA) blocks were designed as described previously ( Article Title: Clinicopathological analysis of claudin 18.2 focusing on intratumoral heterogeneity and survival in patients with metastatic or unresectable gastric cancer Article Snippet: Of the 400 advanced GC cases, 286 surgically collected samples were used to construct Article Title: Bcl-6-dependent risk stratification by nuclear expression of Peli1 in diffuse large B-cell lymphoma Article Snippet: |